E3 Ligase Ligand-Linker Conjugates 2
CAS No. 1818885-63-0
E3 Ligase Ligand-Linker Conjugates 2 ( —— )
产品货号. M28567 CAS No. 1818885-63-0
E3 Ligase Ligand-Linker Conjugates 2 is a synthetic E3 ligase ligand-linker conjugate combining a Pomalidomide-based cereblon ligand and a 4-unit PEG linker.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥413 | 有现货 |
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5MG | ¥672 | 有现货 |
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10MG | ¥988 | 有现货 |
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25MG | ¥1596 | 有现货 |
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50MG | ¥2406 | 有现货 |
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100MG | ¥3686 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称E3 Ligase Ligand-Linker Conjugates 2
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述E3 Ligase Ligand-Linker Conjugates 2 is a synthetic E3 ligase ligand-linker conjugate combining a Pomalidomide-based cereblon ligand and a 4-unit PEG linker.
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产品描述E3 Ligase Ligand-Linker Conjugates 2 is a synthetic E3 ligase ligand-linker conjugate combining a Pomalidomide-based cereblon ligand and a 4-unit PEG linker.
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同义词——
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通路Others
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靶点Other Targets
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受体CCK1
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研究领域——
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适应症——
化学信息
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CAS Number1818885-63-0
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分子量540.6
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分子式C27H32N4O8
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纯度>98% (HPLC)
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溶解度——
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SMILESNc(cc1)ccc1OCCOCCOCCOCCNc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
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NLS-StAx-h
Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
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Ethyl (E)-ferulate
Ethyl ferulate could be used for therapeutic purposes as a potent inducer of HO-1 for the protection of brain cells against oxidative and neurodegenerative conditions.